منابع مشابه
Letter: Hair-metal binding.
reduce the MMT partial pressure to an even smaller value. It is obvious from the above that the po£-sibility of hazardous exposure of customers has to be much lower even than would be the case for TEL. When this is considered in light of the studies of Kehoe et al. in the 1960s on lead alkyls and service station attendants (who would have more exposure than self-service customers) in which it i...
متن کاملAllelic variation in the secreted folate binding protein gene is associated with uterine capacity in swine.
Previous comparisons between the cDNA and gene sequences for secreted folate binding protein (sFBP) indicated a 12-bp insertion/deletion (ins/del) polymorphism in exon 1 and a SNP that altered (Ser-Arg) the protein AA sequence. The effect of the Ser-Arg SNP on reproductive traits was examined in three groups of Meishan-White European breed crossbred gilts. The gilts for all three groups were un...
متن کاملTotal folate binding capacity of normal human plasma, and variations in uremia, cirrhosis, and pregnancy.
The current study presents evidence that all human serum contains a class of high-affinity folate binders (KA=2.8 X10(10 liters/mole), which migrate as a single peak on gel filtration. Failure of previous studies to detect this characteristic in all but a minority of subjects is attributable to its variable, often total, saturation. Direct measurement of the total folate binding capacity (TFBC)...
متن کاملThe mechanism of binding of folate analogues by folate reductase.
The first step in the conversion of folate to the functional form of the vitamin is its reduction to a tetrahydro derivative (1). The enzyme, folate reductase (also called dihydrofolate reductase or tetrahydrofolate dehydrogenase), which catalyzes this reaction has been partially purified from a variety of tissues in different laboratories (2-8). Aminopterin and amethopterin are potent inhibito...
متن کاملBinding characteristics of folate to high affinity folate binding protein purified from porcine serum.
High affinity folate binding protein (HFBP) in porcine serum was purified 2,000-fold to a specific activity of 1.4 nmol of tetrahydrofolic acid (THF) bound per mg of protein, using folic acid (FA) coupled EAH-Sepharose gel affinity chromatography. Binding activity of purified HFBP to folate was examined by ultrafiltration method linked to high-performance liquid chromatography with electrochemi...
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ژورنال
عنوان ژورنال: Blood
سال: 1975
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v46.6.992.992